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Sanitary Pump with Liposome Extruder

Description: The Genizer Online Liposome Extruders attaches to the Genizer Sanitary Pump System to help prepare liposome and lipopolyplex for drug and gene delivery from testing to production scale; Temperature control is available.
Catalog Number: Cat.Nanopump-GOE
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  • Compliance:
    None IQ/OQ FDA 21CFR Compliance SIP/CIP
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  • Description
  • How to Use
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  • Customer Case
Specifications
Description:
 
Genizer online liposome extruder unit is made of pharmaceutical grade 316L stainless steel approved by FDA and GMP and the stainless steel micron-pore supporting mesh guarantees the maximum pressure operation. It's used for production of pharmaceutical liposomes such as anti-cancer drugs from testing to manufacturing scale, with temperature control. Homogenous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size.
The NanoPump (single pump) and PilotPump (dual pumps) help to deliver pressure with high accuracy to force the material to pass through the membrane. They're designed with an intelligent PLC system, which is easy to operate and all parts in contact with medium are 316L stainless steel, 17-4ph stainless steel, titanium alloy, tungsten carbide, PTFE, UHMWPE or other corrosion-resistance materials.
Connecting the Genizer online liposome extruder to the sanitary NanoPump system helps scientists acquire a successful result in their liposome studies and preparation.
 
Application:
 
Liposome extrusion
 
Performance:
 
Easy-control liposome PLC system
Processing temperature and pressure monitoring
 
Specifications for NanoPump (Single Pump)
Catalog No. NanoPump-30 NanoPump-20 NanoPump-16
Max. Flow Rate 30 L/hr 20 L/hr 16 L/hr
Min. Sample Size 80 mL 60 mL 50 mL
Max. Pressure 2500 psi 2500 psi 2500 psi
Dimensions 70 × 36 × 30 cm 70 × 36 × 30 cm 70 × 36 × 30 cm
Weight 40 kg 35 kg 35 kg
Max. Temp. 80 °C (176 °F)
Power 220 V
Cleaning Flush to clean
Application Sanitary pump for liquids in pharmaceutical or biological applications
Features Pressure and temperature transmitters are installed for real-time monitoring
 
Specifications for UltraPump 
Catalog No. UltraPump-60 UltraPump-100
Max. Flow Rate 60 L/hr 100 L/hr
Min. Sample Size 150 mL 200 mL
Max. Pressure 3500 psi 2500 psi
Dimensions 155 × 70 × 50 cm 155 × 70 × 50 cm
Weight 200 kg 200 kg
Max. Temp. 80 °C (176 °F)
Power 380 V or 480 V, 50/60 Hz
Cleaning Flush to clean
Application Sanitary pump for liquids in pharmaceutical or biological applications
Features Pressure and temperature transmitters are installed for real-time monitoring
 
Specifications for PilotPump (Pilot Dual Pumps)
Catalog No. PilotPump-120 PilotPump-200
Max. Flow Rate 120 L/hr 200 L/hr
Min. Sample Size 200 mL 200 mL
Max. Pressure 3500 psi 2500 psi
Dimensions 155 × 105 × 63.5 cm 155 × 105 × 63.5 cm
Weight 350 kg 350 kg
Max. Temp. 80 °C (176 °F)
Power 380 V or 480 V, 50/60 Hz
Cleaning Flush to clean
Application Sanitary pump for liquids in pharmaceutical or biological applications
Features Pressure and temperature transmitters are installed for real-time monitoring
 
Specifications for ProdPump (Prod Dual Pumps)
Catalog No. ProdPump-300 ProdPump-400
Max. Flow Rate 300 L/hr 400 L/hr
Min. Sample Size 400 mL 500 mL
Max. Pressure 3500 psi 2500 psi
Dimensions 175 × 100 × 150 cm 175 × 100 × 150 cm
Weight 800 kg 800 kg
Max. Temp. 80 °C (176 °F)
Power 380 V or 480 V, 50/60 Hz
Cleaning Flush to clean
Application Sanitary pump for liquids in pharmaceutical or biological applications
Features Pressure and temperature transmitters are installed for real-time monitoring
 
Standard Features
Parts Online liposome extruder unit with cooling option
Control System High pressure programming liposome control systems: touch screen, speed control, auto-stop control by pressure or temperature, settable volume control as low as 50mL, display of flow rate and time, overload protection
Indicators Pressure transmitter, temperature Transmitter
Inlet Type 3/8" HIP
Outlet Type 3/4" Tri-Clamp or 1" Tri-Clamp
Feed Reservoir 25 L/50 L Jacketed Vessel, CIP/SIP Optional
Collector Reservoir 25 L/50 L Jacketed Vessel, CIP/SIP Optional
Product Material 316L stainless steel, tungsten carbide, viton, teflon
Material Standard Sanitary grade, FDA, GMP
Warranty 1 year against any manufacturing defects
 
Option Features
Pump/Homogenizer Extruder Sensor Software Capacity
NanoGenizer-6 1×90mm GOE 1 Pres. Liposome Extruder System 1L
NanoPump-16 1×142mm GOE 1 Temp.+1 Pres. Liposome Extruder System 8L
NanoPump-20 2×142mm GOE 2 Temp.+1 Pres. Liposome Extruder System 16L
NanoPump-30 1×293mm GOE 2 Temp.+1 Pres. Liposome Extruder System 20L
PilotGenizer-30 1×293mm GOE 2 Temp.+1 Pres. Liposome Extruder System 20L
UltraPump-60 4×142mm GOE 2 Temp.+1 Pres. Liposome Extruder System 32L
UltraPump-100 8×142mm GOE 2 Temp.+1 Pres. Liposome Extruder System 64L
PilotPump-200 4×293mm GOE 2 Temp.+1 Pres. Liposome Extruder System 80L
PilotPump-200 8×293mm GOE Up to 8 Temp. +1 Pres. Liposome Extruder System 160L
ProdPump-300 8×293mm GOE Up to 8 Temp. +1 Pres. Liposome Extruder System 160L
ProdPump-400 16×293mm GOE Up to 16 Temp. +1 Pres. Liposome Extruder System 320L
 
Product Introduction and User Guide Video Sharing:
Introduction of Jacketed Liposome Extruder
Introduction of HandExtruder
How to make liposomes with HandExtruder

 
1. Order the unit from your Local Agent (Recommended)


2. Add the item into Cart and get the online quote from our website and confirm the order and payment accordingly (Recommended and Economical)
get the quote and Pay offline

3. Email us to get the quote

4. Order and pay online from the website

 


Customer Case: Pilot Liposome Extrusion System
A pharmaceutical company required a pilot-scale liposome extrusion system for liposome formulation development and process scale-up. The project required stable high-pressure performance, sanitary design, and full validation support.

Key Features
  • Up to 2000 psi high-pressure extrusion
  • Dual tank recirculation for uniform particle size
  • Liftable extrusion chamber for fast membrane replacement
  • PLC control with FDA 21 CFR Part 11 compliance
Application Result

Improved particle size consistency and stable processing performance, supporting successful process scale-up.