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Liposome HandExtruder

Description: Hand driven extruder is for formulation of 0.25mL-2.0mL liposome and lipopolyplex; Temperature control is available.
Catalog Number: Cat.HandExtruder
Price:
USD
$1,250.00   Login for Discount
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  • Temperature Control:
    HandExtruder 1mL HandExtruder 1mL-RT
  • Gas Tight Syringe:
    1.0mL*2 0.5mL*2 2.5mL*2
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Specifications
Description:
The HandExtruder is a manually powered extruder designed for the formulation of 0.25mL-2.0mL liposome and lipopolyplex with small samples. The sample is passed back through the membrane by being pushed back and forth between two syringes. Homogenous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. The HandExtruder offers minimal dead-volume, is easy to clean and is suitable for sterilization. Temperature control is available.
 
Application:
Liposome extrusion
 
Performance:
Low dead volume
HandExtruder-1mL-RT can increase the temperature
 
Specifications
Catalog No. HandExtruder-1mL  HandExtruder-1mL-RT
Description Liposome hand extruder Liposome hand extruder with thermo-jacket
Cooling None Yes
Dimensions 23cm×17cm×13cm 23cm×17cm×13cm
Weight 2kg 2kg
Application Liposome formulation Lipids with high transition temperature or heat-sensitive
Min. Sample Size 0.25mL
Max. Pressure 700 psi
Temperature Limit 80ºC (176ºF)
Power Type Manual
Nano-membrane 19mm polycarbonate membrane
Cleaning Flush to clean
Sterilization Whole unit autoclavable
 
Standard Features
Parts 1) Liposome HandExtruder
2) 10 pieces of 100nm membrane
Feed Reservoir 1.0 mL gas-tight syringe
Collector Reservoir 1.0 mL gas-tight syringe
Nano Membrane 100nm 19mm track-etched polycarbonate membrane
Compatibility Parts are compatible with Liposofast in Avestin
Product Material 316L stainless steel, viton
Material Standard Sanitary grade
Warranty 1 year against any manufacturing defects
 
Option Features
Parts Stabilizer holder for HandExtruder
Feed Reservoir 0.25/0.5/1.0/2.5mL gas-tight syringe
Collector Reservoir 0.25/0.5/1.0/2.5mL gas-tight syringe
Nano Membrane 30, 50, 80, 100, 200, 400, 800nm, 1000nm, 2μm, 5μm, 10μm, 20μm, 30μm 19mm track-etched membrane
Syringe Type Gas-tight syringe with protective film
 
Laboratory Instruction of the Manual Liposome Extruder
 
Liposome HandExtruder
Disassemble the HandExtruder, load 1-2 pieces of liposome extruding nano-pore membrane
 

Liposome HandExtruder
Connect the gas-tight syringes (0.25mL, 0.5mL, 1mL, 2.5mL) at both ends
 
Liposome HandExtruder
Load the sample and extrude by pressing back and forth 10 times

 
Liposome HandExtruder
Extruding through 800, 400nm, 200nm, 100nm (if needed 80nm, 50nm, 30nm) nano-pore membranes
Considering the limitations of the durability of POM plastic, can the filter chamber be customized with metal material?
Of course, we recommend 316L filter chamber. The stainless steel luer lock is more durable. And the hygienic property, low expansion coefficient, high thermal conductivity, and  hardness of this material can improve the user's experience.

filter chamberfilter chamber