Operating Genizer homogenizers and extruders involves handling samples at high pressure. Therefore, it is crucial to follow the operation instructions carefully to prevent personal injury from disregarding the instructions or equipment damage from improper handling. DO NOT proceed until the operator has thoroughly read and understood the instructions provided in the associated User Guide. Additionally, wearing personal protective equipment is recommended during operation, and the high pressure homogenizer and extruder are recommended to be operated in the shielded hood or space.