Choosing a Homogenizer

  A homogenizer is a tool that is widely used in the food industry. Consumers want consistency in their prepackaged foods, so food manufacturers use the homogenizer to ensure that their ingredients are mixed together in an even way. Homogenizers are used in large batches to ensure that materials are evenly blended.

high pressure homogenizer

  High-pressure homogenizers are a useful piece of equipment for a number of different applications. Before choosing one, however, it's important to know what you'll be homogenizing, how much the product needs to be processed, and the general operating environment. In addition, you should also know what pressure you'll be homogenizing at. Most end users have a general idea of what pressure they need, and can therefore use this information to select the right machine.

  High-pressure homogenizers allow for greater consistency in composition and dissolution of active ingredients in a pharmaceutical product. By creating a uniform dispersion of active ingredients in syrup or pill form, they enable the final product to be more stable and less prone to degradation and contamination. In addition, using a high-pressure homogenizer also eliminates the costs associated with product recalls.

  However, high-pressure homogenizers come with a number of disadvantages. For example, they are bulky and heavy, and can cost up to tens of thousands of dollars. Most importantly, however, they are difficult to clean, and need to be cleaned after each use. Furthermore, the valves of a high-pressure homogenizer can get clogged up when the liquid sample contains higher solids.

  An impact valve is another component of a high-pressure homogenizer. This feature helps reduce local wear and extend the service life of the homogenization chamber. The principle behind this valve is that the material in suspension is impacted against a high-hard metal surface. However, the impact valve cannot solve the problem of metallic particle residues. By the first decade of the twentieth century, most high-pressure homogenizers were equipped with an impact valve.

laboratory homogenizer

  Laboratory homogenizers are used for mixing, dispersing and blending chemical, biological and environmental samples. These devices are often used in the life science and pharmaceutical industries, for example, to make a lysate, extract protein, or dissolve a solid sample in a liquid. Other applications include mixing immiscible materials and dispersing chemical compounds.

  Various types of laboratory homogenizers are available, with the best ones suited to the specific application. Some are designed for processing small volumes, while others are intended for large-scale production. There are two types of homogenizers: benchtop and ultrasonic. The latter is designed for high throughput applications and has a streamlined design.

  The first type of homogenizer uses capillary tubes and concave valves. A capillary tube throttles the pressure of the fluid, while the concave valve acts as a kinetic impact surface for the fluid jet. The more advanced designs have seats that mate with the valve at an appropriate clearance. The small gap in the valve allows for the fluid flow necessary to homogenize the sample.

  High throughput homogenizers handle multiple samples at once. However, the probe must be cleaned after each sample, thereby increasing the chance of cross contamination. Moreover, a homogenizer is not appropriate for processing samples containing bacteria, fungi, yeast, and thick walls.

high pressure homogenizer principle

  High pressure homogenizers work by applying pressure on a solid or liquid material to swell it. These machines can handle a wide range of sample sizes. They are also capable of either batch or continuous processing. Some models have the ability to make multiple passes, while others are designed for single passes. When choosing a high pressure homogenizer, consider the amount of cleaning required.

  A high-pressure homogenizer works by forcing a stream of liquid through a narrow nozzle at high pressure, usually 400 MPa. This creates a large amount of shear stress, which emulsifies and lyses sample components. The smaller the nozzle aperture, the smaller the droplets will be. This process can also result in particle sizes as small as nanometers. High pressure homogenizers are often used in the dairy industry to process large volumes of liquid samples.

  A high-pressure homogenizer has two main components: the high-pressure pump unit and the homogenization unit. The pump unit includes a special diamond interaction chamber. The pistons in the pump unit drive the samples through the chamber at high-speed. This causes the materials in the chamber to be subjected to various mechanical forces, such as high-frequency oscillation, high-shear, and convective impact. These mechanical effects change the particle structure and result in uniform nanoparticle size.

  High-pressure homogenizers are used in various industries to produce emulsions and suspensions. They are used to reduce particle size and add value to a product. However, high-pressure homogenizers are prone to clogging.